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Title : Dr.
Last Name : ERICKSON
University/Institution : University of Colorado
Email ID : christopher.erickson@cuanschutz.edu
City : Aurora
Country : United States
State : Colorado
Zipcode : 80045
Department : Biochemistry and Molecular Genetics
Company Name :
Area of Research
Proteomics, Bioinformatics
Area of Expertise
Proteomics, Bioinformatics, Tissue engineering, Regenerative medicine, Orthopedic biology
Brief Description of Research Interest :
My research interests lie in developing informatics tools for studying proteomics and proteogenomics, two fields that illuminate our understanding of health and disease phenotype. There have been great advances in proteomics technology and workflows that enable researchers to understand more about the phenotype of their samples of interest. However, the informatics tools currently used for this lag far behind the current technology's ability to identify and quantify proteins. Further compounding this issue is the steep learning curve required to operate and understand these tools. My specific goals in this area of research are to develop tools that 1) advance library-free DIA proteomics (will enhance proteome identification/quantification), and 2) enable more researchers to study health and disease using proteogenomics. Studying the proteome with respect to the genome (and vice versa) offers a unique and comprehensive perspective. Given that few of these tools exist, my work in this area aims to develop software tools that researchers can use for proteogenomics. 

Additionally, I have an extensive background in tissue engineering and regenerative medicine (TERM). I always have aspirations to design TERM oriented treatments, and am actively developing naturally derived ECM scaffolds for this purpose. 
Representative Publications :

§ Erickson CB, Newsom JP, Fletcher NA, Yu Y, Rodriguez-Fontan F, Weatherford SA, Hadley-Miller N, Krebs MD, Payne KA. “Local delivery of anti-VEGF antibody attenuates bony bar formation following physeal injury.” JOR, Submitted June 2020.

§ Payne KA, Shaw NM, Erickson CB, Peter Yarger PJ, Yu Y, Baldini T, Kleck CJ, Patel VV, Burger EL. “Blockade of Osteoclast-Mediated Bone Resorption with a RANKL Inhibitor Enhances Spinal Fusion in a Rat Model.” JBJS, Under revision March 2020.

§ Erickson CB, Newsom JP, Fletcher NA, Feuer ZM, Yu Y, Rodriguez-Fontan F, Hadley-Miller N, Krebs MD, Payne KA. “In vivo degradation rate of alginate-chitosan hydrogels influences tissue repair following physeal injury.” Journal of Biomedical Materials Research Part B. Accepted. Article DOI: 10.1002/jbm.b.34580.

§ Erickson CB, Payne KA. "Inductive signals and progenitor fates during osteogenesis." Encyclopedia of Tissue Engineering and Regenerative Medicine, Reference Module in Biomedical Sciences. 2018, Elsevier ISBN: 978-0-12-801238-3.

§ Shaw N, Erickson CB, Bryant SJ, Ferguson VL, Krebs MD, Hadley-Miller N, Payne KA. "Regenerative Medicine Approaches for the Treatment of Pediatric Physeal Injuries." Tiss Eng Part B Rev. 2018 Apr;24(2):85-97.

§ Erickson CB, Shaw N, Hadley-Miller N, Riederer MS, Krebs MD, Payne KA. "A Rat Tibial Growth Plate Injury Model to Characterize Repair Mechanisms and Evaluate Growth Plate Regeneration Strategies." J Vis Exp. 2017 Jul 4:(125).

§ Hernandez T, Bessesen DH, Cox-York KA, Erickson CB, Law C, Anderson M, Wang H, Jackman M, Van Pelt RE. "Femoral lipectomy increases postprandial lipemia in women." Am J Physiol Endocrinol Metab. 2015 Jul 1;309(1):E63-71.