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EDITORIAL BOARD
 
  Dr. MUTHUKUMAR BALASUBRAMANIAM  
 
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Title : Dr.
First Name : MUTHUKUMAR
Last Name : BALASUBRAMANIAM
University/Institution : Meharry Medical College
Email ID : muthukumarb@mmc.edu
City : Nashville
Country : United States
State : Tennessee
Zipcode : 37208
Department : Center for AIDS Health Disparities Research
Company Name :
Area of Research
Molecular Virology
Area of Expertise
HIV/AIDS
Brief Description of Research Interest :

My scientific research interests have largely revolved around virus-host interactions. My pre-doctoral research training involved molecular characterization of a DNA virus causing the most devastating viral disease in bananas. In my doctoral research work at Purdue University, I identified and characterized novel virus-host protein interactions that modulate the replication of an RNA virus reported to infect over 600 plant species. During my NIH postdoctoral fellowship at the National Cancer Institute, I researched novel components of the host cellular machinery involved in late stages of HIV-1 replication. In my current position as a postdoctoral research associate at Meharry Medical College, my research interests include key early events leading to HIV-1 integration into host chromosome, role of microRNAs in regulating cellular cofactors of HIV-1, and the impact of drugs of abuse on HIV-1 replication and pathogenesis.


Editor, Vaccines (Topic Board)


GuestEditor, Special Issue "New Insights into HIV-Host interactions", Vaccines


SoLS Interview: Dr. Roger Chalkley (Vanderbilt University): http://societyoflifesciences.org/article-member.aspx?id=2


SoLS Interview: Dr. Joanne Kamens (Addgene): http://societyoflifesciences.org/article-member.aspx?id=1013


Representative Publications :
 

Balasubramaniam, M., Pandhare, J., Dash, C. 2019. Immune control of HIV. JoLSJournal of Life Sciences 1(1), June 2019:4-36.


Davids, BO., Balasubramaniam, M., Sapp, N., Prakash, P., Ingram, S., Li, M., Craigie, R., Hollis, T., Pandhare, J., Dash, C. 2021. Human three primerepair exonuclease 1 promotes HIV-1 integration by preferentially degrading unprocessed viral DNA. Journal of Virology.10.1128/JVI.00555-21


Jones, B., Balasubramaniam, M., Lebowitz, JJ., Villalta, F., Khoshbouei, H., Dash, C., Pandhare, J. 2021. Activation of proline biosynthesis is critical to maintain glutamate homeostasis during acute methamphetamine exposure. Scientific Reports.11:1422


Chaudhuri, E*., Dash, S*., Balasubramaniam, M*., Holland, OL., Villalta, F., Engelman, A., Pandhare, J., Dash, C. 2020. The HIV-1 capsid binding host factor CPSF6 is post transcriptionally regulated by the cellular microRNA miR-125b. Journal of Biological Chemistry 295(15):5081-5094

*These authors have contributed equally


Balasubramaniam, M., Zhou, J., Addai, A., Martinez, P., Pandhare, J., Aiken, C., Dash, C. 2019. PF74 inhibits HIV-1 integration by altering the composition of the preintegration complex. Journal of Virology.10.1128/JVI.01741-18.


Ysrayl, B., Balasubramaniam, M., Albert, I., Villalta, F., Pandhare, J., Dash, C. 2019. A novel role of prolidase in cocaine-mediated breach in the barrier of brain microvascular endothelial cells. Scientific Reports 9:2567

 

Balasubramaniam, M., Pandhare, J., Dash, C. 2018. Are microRNAs important players in HIV-1 infection? An update. Viruses 10(3):110.


Novikova, M., Adams, L.,Fontana, J., Gres, A., Balasubramaniam, M., Winkler, D.,Kudchodkar, S.,Soheilian, F., Sarafianos, S., Steven, A., Freed, E. 2018. Identification of a structural element in HIV-1 Gag required for virus particle assembly and maturation. mBio. 9:e01567-18.


Dash S., Balasubramaniam, M., Rana, T.,Godino, A., Peck, E. E., Goodwin, J. S., Calipari, E. S., Villalta, F., Nestler, E. J., Dash, C., Pandhare J. 2017. Poly (ADP-ribose) polymerase-1 (PARP-1) induction by cocaine is post-transcriptionally regulated by miR-125b. eNeuro August 2017, 4(4) e0089-17.2017 1-15

 

Balasubramaniam, M., Kim, BS., Hutchens-Williams HM.,Loesch-Fries, S. 2014. The photosystem II oxygen evolving complex protein, PsbP,  interacts with the coat protein of Alfalfa mosaic virus and inhibits its replication. Molecular Plant Microbe Interactions 27(10):1107-18.

 

Balasubramaniam, M., Freed, E. O. 2011. New insights into HIV assembly and trafficking. Physiology 26:236-251.

 

Balasubramaniam, M., Ibrahim, A., Kim, BS., Loesch-Fries,S. 2006. Arabidopsis thaliana is an asymptomatic host of Alfalfa mosaic virus. Virus Research 121:215-219.

 

 
     
 
 
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