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Title : Dr.
First Name : SHREYA
University/Institution : UMass Medical School
Email ID : shreyaroychowdhury@ymail.com
City : shrewsbury
Country : United States
State : Massachusetts
Zipcode : 01545
Department : Molecular Cell and Cancer Biology
Company Name :
Area of Research
Genetic screen based on CRISPR
Area of Expertise
cellular and molecular biology, metabolomics, cancer biology
Brief Description of Research Interest :

Shreya has been working in the field of cancer for a long time. She has worked on deciphering the mechanisms underlying growth-factor induced metastasis in ovarian cancer cells and has expertise in various molecular biology techniques including PCR, western blotting, microscopy, mammalian cell culture, cloning, flow cytometry, to name a few. Shreya has also worked from the perspective of cellular energetics.

Currently, Shreya is working on identifying epigenetic factors regulating expression of a tumor-suppressor using CRISPR based genetic screening to identify the factors. She is mostly involved in making reporter cell-lines, crispr screening library usage, cloning etc.

Representative Publications :
1. Chowdhury SR, Ray U, Chatterjee BP, Roy SS. Targeted apoptosis in ovarian cancer cells throughmitochodnrial dysfunction in response to Sambucus nigra agglutinin. Cell Death and Disease. 2017May 4;8(5):e2762. doi: 10.1038/cddis.2017.77.

2. Ray U, Roy Chowdhury S, Roy SS. Lysophosphatidic Acid Promotes Epithelial to MesenchymalTransition in Ovarian Cancer Cells by Repressing SIRT1. Cell Physiol Biochem. 2017Feb14;41(2):795-805.

3. Ray U, Roy Chowdhury S, Vasudevan M, Bankar K, Roychoudhury S, Roy SS. Gene regulatorynetworking reveals the molecular cue to lysophosphatidic acid-induced metabolic adaptations inovarian cancer cells. Molecular Oncology. 2017 Feb 25. doi: 10.1002/1878-0261.12046.

4. Karthikeyan Thirugnanam, Stephanie Cossette, Qiulun Lu, Shreya R. Chowdhury, Leanne M.Harmann, Dmitry L. Sonin, Michelle Bordas, Ankan Gupta, Andrew Spearman, Suresh N. Kumar,Jennifer L. Strande, Erin Bishop, Ming-Hui Zou, and Ramani Ramchandran. Cardiomyocyte-specificSNRK prevents inflammation in the heart. J Am Heart Assoc. 2019 Nov 19;8(22):e012792.doi: 10.1161/JAHA.119.012792.
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