Dr. SHREYA ROY CHOWDHURY
 
 
First Name
SHREYA
Last Name
ROY CHOWDHURY
University/Institution
UMass Medical School
Email ID
shreyaroychowdhury@ymail.com
City
shrewsbury
Country
United States
State
Massachusetts
Zip code
01545
Department
Molecular Cell and Cancer Biology
Area of Research
Genetic screen based on CRISPR
Area of Expertise
cellular and molecular biology, metabolomics, cancer biology
Brief Description of Research Interest:
 

Shreya has been working in the field of cancer for a long time. She has worked on deciphering the mechanisms underlying growth-factor induced metastasis in ovarian cancer cells and has expertise in various molecular biology techniques including PCR, western blotting, microscopy, mammalian cell culture, cloning, flow cytometry, to name a few. Shreya has also worked from the perspective of cellular energetics.


Currently, Shreya is working on identifying epigenetic factors regulating expression of a tumor-suppressor using CRISPR based genetic screening to identify the factors. She is mostly involved in making reporter cell-lines, crispr screening library usage, cloning etc.

 
Representative Publications:
 
1. Chowdhury SR, Ray U, Chatterjee BP, Roy SS. Targeted apoptosis in ovarian cancer cells throughmitochodnrial dysfunction in response to Sambucus nigra agglutinin. Cell Death and Disease. 2017May 4;8(5):e2762. doi: 10.1038/cddis.2017.77.

2. Ray U, Roy Chowdhury S, Roy SS. Lysophosphatidic Acid Promotes Epithelial to MesenchymalTransition in Ovarian Cancer Cells by Repressing SIRT1. Cell Physiol Biochem. 2017Feb14;41(2):795-805.

3. Ray U, Roy Chowdhury S, Vasudevan M, Bankar K, Roychoudhury S, Roy SS. Gene regulatorynetworking reveals the molecular cue to lysophosphatidic acid-induced metabolic adaptations inovarian cancer cells. Molecular Oncology. 2017 Feb 25. doi: 10.1002/1878-0261.12046.

4. Karthikeyan Thirugnanam, Stephanie Cossette, Qiulun Lu, Shreya R. Chowdhury, Leanne M.Harmann, Dmitry L. Sonin, Michelle Bordas, Ankan Gupta, Andrew Spearman, Suresh N. Kumar,Jennifer L. Strande, Erin Bishop, Ming-Hui Zou, and Ramani Ramchandran. Cardiomyocyte-specificSNRK prevents inflammation in the heart. J Am Heart Assoc. 2019 Nov 19;8(22):e012792.doi: 10.1161/JAHA.119.012792.