Dr. PHU KHAT NWE | Journal of Life Sciences (JoLS)

Dr. PHU KHAT NWE

First Name

PHU KHAT

Last Name

NWE

University/Institution

Yale University

Email ID

phukhat.nwe@gmail.com

City

San Diego

Country

United States

State

California

Zip code

92122

Department

Chemistry/ Chemical Biology

Area of Research

chemical biology, microbiology & molecular biology

Area of Expertise

Profiling of microbial gut metabolites in relation to G-Protein Coupled Receptors

Brief Description of Research Interest:

My research background falls at the interface of microbiology, molecular biology and chemical biology. My PhD research focused on structurally and functionally profiling small molecule metabolites from gut microbes in relation to the activation of G-Protein Coupled Receptors (GPCRs). In addition, I implemented an biochemical assay platform to study a genotoxic gene cluster implicated in colorectal cancer. Overall, I am interested in the discovery and development of small molecules that have implications in diseases and therapeutics.

Representative Publications:

Â· Chen, H.; Nwe, P.-K.; [â€¦]; Crawford, J.M.; Palm, N.W. A Forward Chemical Genetic Screen Reveals Gut Microbiota Metabolites that Modulate Host Physiology. Cell, 2019, 177 (5): 1217-1231.

Â· Shine, E.E.; Nwe, P.-K.; Crawford, J.M. Chemistry and Enzymology Encoded by the Human Microbiome. Reference Module in Chemistry, Molecular Sciences and Chemical Engineering, Elsevier, 2019,ISBN 9780124095472

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