Dr. JAY HOU
 
 
First Name
JAY
Last Name
HOU
University/Institution
University of Minnesota
Email ID
chiehhou@gmail.com
City
Minneapolis
Country
United States
State
Minnesota
Zip code
55455
Department
Biomedical Engineering
Area of Research
biophysics and biomechanics of cancer cell migration in tissue
Area of Expertise
stochastic modeling, finite element modeling, cell migration microscopy, tissue mechanical testing
Brief Description of Research Interest:
 
I am interested in biophysical mechanisms of cancer cell migration affected by intracellular protein levels, biomechanics of 3D hydrogels and tissues based on their biochemical components, and interactions between cell migration mechanisms and 3D tissue mechanics. 
 
Representative Publications:
 
J. C. Hou, G. A. Shamsan, S. M. Anderson, M. M. McMahon, L. P. Tyler, B. T. Castle, R. K. Heussner, P. P. Provenzano, D. F. Keefe, V. H. Barocas, and D. J. Odde. Modeling distributed forces within cell adhesions of varying size on continuous substrates,    Cytoskeleton, 76(11-12), 2019
J. C. Hou, S. A. Maas, J. A. Weiss, and G. A. Ateshian. Finite Element Formulation of Multiphasic Shell Elements for Cell Mechanics Analyses in FEBio. Journal of Biomechanical Engineering, 140(12):121009, 2018 
C. Hou and G. A. Ateshian, A Gauss-Kronrod-Trapezoidal Integration Scheme for Modeling Biological Tissues with Continuous Fiber Distributions, Computer Methods in Biomechanics and Biomedical Engineering,19(8), 883-893, 2015
B. Mohanraj, C. Hou, G. R. Meloni, B. D. Cosgrove, G. R. Dodge, and R. L. Mauck, A High Throughput Mechanical Screening Device for Cartilage Tissue Engineering, Journal of Biomechanics, 47(9, SI): 2130-2136, 2014
L. Bian, C. Hou, E. Tous, R. Rai, R. L. Mauck, and J. A. Burdick, The Influence of Hyaluronic Acid Hydrogel Crosslinking Density and Macromolecular Diffusivity on Human MSC Chondrogenesis and Hypertrophy, Biomaterials, 34(2): 413-421, 2013