MEMBER PROFILE
| First Name | Laura |
| Last Name | Rodriguez-Castro |
| University/Institution | University of Wisconsin-Madison |
| Email ID | [email protected] |
| City | Madison |
| Country | United States |
| State | Wisconsin |
| Zip code | 53726 |
| Department | |
| Area of Research | Enviromental Microbiology |
| Area of Expertise | Microbiology, Molecular Biology, Biotechnology |
Brief Description of Research Interest :
My research is focused on unraveling the role of transcriptional regulators in the aromatic catabolic pathways of Novosphingobium aromaticivorans DSM12444. This strain is able to produce the bioplastic precursors 2-pyrone-4,6-dicarboxylic acid (PDC) and cis,cis-muconic acid (ccMA) as intermediates of aromatics catabolism. Understanding the regulation of these pathways is crucial to improve the bioplastics production process.
Representative Publications:
- Durán RE, Méndez V, Rodríguez-Castro L, Barra-Sanhueza B, Salvà-Serra F, Moore ERB, Castro-Nallar E, and Seeger M (2019) Genomic and Physiological Traits of the Marine Bacterium Alcaligenes aquatilis QD168 Isolated From Quintero Bay, Central Chile, Reveal a Robust Adaptive Response to Environmental Stressors. Front. Microbiol. 10:528. doi: 10.3389/fmicb.2019.00528.
- Rodríguez-Castro L, Méndez V, Durán RE, Seeger M (2019) Long-chain flavodoxin FldX1 improves Paraburkholderia xenovorans LB400 tolerance to oxidative stress caused by paraquat and H2O2. PLoS ONE 14(8): e0221881. https:// doi.org/10.1371/journal.pone.0221881.
- Macaya CC, Durán RE, Hernández L, Rodríguez-Castro L, Barra-Sanhueza B, Dorochesi F, Seeger M. Bioremediation of Petroleum. In: Reference Module in Life Sciences, Elsevier, 2019, ISBN: 978-0-12-809633-8, http://dx.doi.org/10.1016/B978-0-12-809633-8.20810-8.
- Rodríguez-Castro L, Durán RE, Macaya CC, Dorochesi F, Hernández L, Salazar-Tapia F, Ayala-Espinoza V, Santis-Cortés P, Báez-Matus X, Seeger M. Novel insights in petroleum bioremediation of polluted environments and bacterial catabolic pathways in Hydrocarbon Biotechnology: Challenges and Future Trends. November 2022 (https://www.appleacademicpress.com/title.php?id=9781774639894).
- Méndez, V., Rodríguez-Castro, L., Durán, R.E. et al. The OxyR and SoxR transcriptional regulators are involved in a broad oxidative stress response in Paraburkholderia xenovorans LB400. Biol Res 55, 7 (2022).
- Rodríguez-Castro, L., Durán, R.E., Méndez, V. et al. The long-chain flavodoxin FldX1 improves the biodegradation of 4-hydroxyphenylacetate and 3-hydroxyphenylacetate and counteracts the oxidative stress associated to aromatic catabolism in Paraburkholderia xenovorans. Biol Res 57, 12 (2024).