MEMBER PROFILE

Dr. PAULA SANCHEZ MOLINA
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First Name PAULA
Last Name SANCHEZ MOLINA
University/Institution OHSU
Email ID [email protected]
City Portland
Country United States
State Oregon
Zip code 97239
Department Molecular Microbiology and Immunology
Area of Research Immunity in neurodegeneration
Area of Expertise Neuroimmunology

Representative Publications:

Sanchez-Molina, P., Kreuzer, M., Benseny-Cases, N., Valente, T., Almolda, B., González, B., Castellano, B., Perálvarez-Marín, A. (2020). From mouse to human: Comparative analysis between grey and white matter by synchrotron-Fourier transformed infrared microspectroscopy. Biomolecules10(8), E1099. 

Sanchez-Molina, P., Almolda, B., Benseny-Cases, N., González, B., Perálvarez-Marín, A., Castellano, B. (2021). Specific microglial phagocytic phenotype and decrease of lipid oxidation in white matter areas during aging: implications of different microenvironments. Neurobiology of Aging, 105, 280-295.

Sanchez-Molina, P*., Almolda, B., Giménez-Llort, L., González, B., Castellano, B. (2022). Chronic IL-10 overproduction disrupts microglia-neuron dialogue similar to aging, resulting in impaired hippocampal neurogenesis and spatial memory. Brain, Behavior, and Immunity101, 231-245. *Corresponding author.

Sanchez-Molina, P., Pratapa, A., Nikulina, N., Cheikh, BB., Singh, J., Dhawan, A., Bogachuck, A., Chiot, A., Chin, G., Emberley, K., Crotti, A., Woltjer, R., Braubach, O., Ajami, B. (2023). Single-cell spatial proteomic analysis by multiplexed imaging enables identification of microglial heterogeneity in Alzheimer’s disease human brain. PREPRINT (Version 1) available at Research Square.

Soto-Faguás, C.M., Sanchez-Molina, P., Saura, C.A. (2021). Loss of presenilin function enhances tau phosphorylation and aggregation in mice. Acta Neuropathologica Communications, 9, 162.

Enrich-Bengoa, J., Manich, G., Valente, T., Sanchez-Molina, P., Almolda, B., Solà, C., Saura, J., González, B., Castellano, B., Perálvarez-Marín, A. (2022). TRPV2: A Key Player in Myelination Disorders of the Central Nervous System. International Journal of Molecular Sciences, 23, 3617.

Evans, F., Alí-Ruiz, D., Rego, N., Negro-Demontel, M. L., Lago, N., Cawen, F. A., Pannunzio, B., Sanchez-Molina, P., Reyes, L., Paolino, A., Rodríguez-Duarte, J., Pérez-Torrado, V., Chicote-González, A., Quijano, C., Marmisolle, I., Mulet, A. P., Schlapp, G., Meikle, M. N., Bresque, M., Crispo, M., … Peluffo, H. (2023). CD300f immune receptor contributes to healthy aging by regulating inflammaging, metabolism, and cognitive decline. Cell reports42(10), 113269.

Kodali, M., Antone, J., Alsop, E., Jayakumar, R., Parikh, K., Sanchez-Molina, P.Ajami, B., Arnold, S., Jensen, K., Das, S.,Weinberg, M.S. (2023). Cryopreservation of cerebrospinal fluid cells preserves transcriptomics integrity for single-cell analysis. bioRxiv.