Representative Publications:
The full spectrum of human naïve T cells.
van den Broek T, Madi A, Delemarre EM, Schadenberg AWL, Tesselaar K, Borghans JAM, Nierkens S, Redegeld FA, Otten HG, Rossetti M, Albani S, Sorek R, Cohen IR, Jansen NJG, van Wijk F.
Human neonatal thymectomy induces altered B-cell responses and autoreactivity.
Eur J Immunol. 2017 Nov;47(11):1970-1981. doi: 10.1002/eji.201746971. PubMed PMID: 28691750; PubMed Central PMCID: PMC5697610.
van den Broek T, Delemarre EM, Janssen WJ, Nievelstein RA, Broen JC, Tesselaar K, Borghans JA, Nieuwenhuis EE, Prakken BJ, Mokry M, Jansen NJ, van Wijk F. Neonatal thymectomy reveals differentiation and plasticity within human naive T cells. J Clin Invest. 2016 Mar 1;126(3):1126-36. doi: 10.1172/JCI84997. PubMed PMID: 26901814; PubMed Central PMCID: PMC4767338. Delemarre EM*, van den Broek T*, Mijnheer G, Meerding J, Wehrens EJ, Olek S, Boes M, van Herwijnen MJ, Broere F, van Royen A, Wulffraat NM, Prakken BJ, Spierings E, van Wijk F. (*contributed equally)
Autologous stem cell transplantation aids autoimmune patients by functional renewal and TCR diversification of regulatory T cells.
Blood. 2016 Jan 7;127(1):91-101. doi: 10.1182/blood-2015-06-649145. PubMed PMID: 26480932.