1) LASELVA O., DU K, BEAR C.E Activity of Lumacaftor is not conserved in zebrafish Cftr bearing major CF-causing mutation (FASEB J, in revision)
2) LASELVA O., MARZARO G., VACCARIN C., LAMPRONTI I., TAMANINI A., LIPPI G., GAMBARI R., CABRINI G., BEAR C.E., CHILIN A., DECHECCHI M.C.;Molecular mechanism of action of Trimethylangelicin derivatives as CFTR modulators(Frontiers in Pharmacology, 2018)
3) LASELVA O., MOLINSKI S., CASAVOLA V., BEAR C.E. Correctors of the major Cystic Fibrosis mutant interact through membrane spanning domains (Molecular Pharmacology, 2018)
4) MOLINSKI S., SHAHANI V., SUBRAMANIAN A., MACKINNON S., WOOLLARD G., LAFORET M., LASELVA O., MORAYNISS L., BEAR C.E., WINDEMUTH A., Comprehensive mapping of Cystic Fibrosis mutations to CFTR protein identifies mutation clusters and molecular docking predicts corrector binding site (Proteins: Structure, Function, and Bioinformatics, 2018)
5) MOLINSKI S., AHMADI S., KULLEPERUMA K., IP W., OUYANG H., VILLELLA A., MILLER J.P., LEE P.S, KULLEPERUMA K., DU K, DI PAOLA M., ECKFORD P., LASELVA O., HUAN L.J., WELLHAUSER L, LI E., RAY P.N, MORAES T.J. GONSKA T., RATJEN F, BEAR C.E. ORKAMBI/amplifier co-therapy rescues a rare CFTRmutation in gene-edited cells and patient tissue (Embo Molecular Medcine, 2017)
6) LASELVA O., MOLINSKI S., CASAVOLA V., BEAR C.E. The investigational Cystic Fibrosis drug Trimethylangelicin directly modulates CFTR by stabilizing the first membrane-spanning domain (Biochemical Pharmacology Journal, 2016)
7) ABBATTISCIANNI A.C., FAVIA M, MANCINI M.T., CARDONE R.A., GUERRA L., MONTERISI S., CASTELLANI S., LASELVA O., DI SOLE F., CONESE M., ZACCOLO M., CASAVOLA V. “Correctors of mutant CFTR enhance subcortical cAMP/PKA signaling via ezrin phosphorylation and cytoskeleton organization (Journal of Cell Science, 2016)
8) FAVIA M, MANCINI MT, BEZZERRI V, GUERRA L, LASELVA O, ABBATTISCIANNI A.C, RESHKIN SJ, GAMBARI R, CABRINI G, CASAVOLA V. Trimethylangelicin promotes the functional rescue of F508del CFTR in CF airway cells. (Am J Physiol Lung Cell Mol Physiolgy 2014)